Saturday sees matches played in the last 32 of the national FAW Trophy.
Here is a look at all the ties involving northern teams.
Round four previews (1.30 pm kick-offs)
Bodedern Athletic v Holyhead Hotspur
A much-awaited island derby sees sixth host second in Welsh Alliance Division One.
Meetings between these two have been rare over the years, with Hotspur having spent seven seasons in the Cymru Alliance before dropping back into the third-tier this term.
Bodedern battled their way back into Welsh Alliance Division One last season after a four-year absence and finished runners-up.
The last time both clubs were at their present league level was 2011-12.
Both sides offer plenty in attack – Boded in the shape of Dean Redmond and Aidan Clark, while the likes of Robert Jones and Chris Jones are confirmed dangers for Hotspur.
Carno v Llandudno Albion
Carno are 10th in Mid-Wales League Division One, while Albion lie third in Welsh Alliance Division One and are shaping into potential title challengers.
Both scraped through 3-2 in the third round, Carno over Bow Street and Albion at the expense of battling minnows Mynydd Isa Spartans.
Worthy of note, however, is the fact Carno have already eliminated Mid-Wales League leaders Llanidloes Town away in this competition.
Cefn Mawr Rangers v Welshpool Town
After causing the upset of the third round by winning 2-0 at Welsh Alliance Division One Greenfield, Rangers will be out to produced another surprise by seeing off Mid-Wales Division One high-flyers Welshpool.
With home advantage, the Welsh National League Division One hosts have no reason to believe they cannot weave their magic again. A big day for Daniel Richards’ side.
Lex XI v Berriew
Having dumped out the holders Cefn Albion in round two, then eliminated Gwynedd League champions Menai Bridge Tigers at the last stage, Lex can carry plenty of confidence into their meeting with Berriew, seventh in Mid-Wales Division One.
Llay Welfare v Llanrwst United
Very hard one to call with both teams capable of big performances on their day.
Llanrwst will no doubt have been massively boosted by last weekend’s 5-1 thrashing of Holyhead Hotspur in Welsh Alliance Division One.
The Rwsters also made the news after halting Bangor 1876’s 13-match winning run in all competitions in the last round.
Llay battered Llandudno Athletic 9-1 in round three, so there could be some goals in store.
Llanrug United v Brymbo
Two former Trophy winners come into combat at Eithin Duon.
Llanrug claimed an emphatic 5-1 victory at Llanuwchllyn in the previous round, while Brymbo are considered major contenders for the Welsh National League Premier Division crown.
One of the ties of the round for sure.
Nantlle Vale v Barmouth and Dyffryn
Barmouth advanced emphatically in round three with a 4-0 triumph at Llandudno Junction, but could find the going tougher away to Welsh Alliance Division One hosts Nantlle.
Nefyn United v Denbigh Town
Gwynedd League Nefyn aim for a fifth giant-killing of the season when Welsh Alliance Division One table-toppers Denbigh arrive at Cae’r Delyn.
The Penwaig have already knocked Welsh Alliance sides Penmaenmawr Phoenix and Llannefydd out of the Trophy, as well as third and fourth tier Mynydd Llandegai and Llandudno Amateurs respectively from the Welsh Cup.
Now comes perhaps the biggest test of all although Denbigh have already been victims of a shock this season, going out of the Welsh Cup at home to tier-four Mynydd Isa Spartans.
Denbigh manager Dewi Llion is certainly taking the challenge of Nefyn seriously, saying: “Nefyn will be a difficult team to beat. They have some excellent players and it shows in their results this season. Beating Llannefydd away is an achievement in itself as they are very strong this year.
“Regardless of the gap in league standings we certainly won’t be taking them lightly.”
Radnor Valley v Mold Alexandra
In the lower reaches of Mid-Wales League Division One, Radnor nonetheless merit respect, especially after their 5-4 extra time victory at Caersws in the last round.
Mold have been going great guns in the WNL Premier, and have been outstanding in the cups, but suffered a jolt when losing 4-3 at home to Saltney Town last weekend.
Rhos Aelwyd v Gaerwen
Beaten finalists in 2018, Rhos Aelwyd caused quite a stir in the last round by winning 4-2 against the odds at Rhostyllen.
Gaerwen are having their best-ever season in Division Two of the Welsh Alliance and have to be considered as having a fair chance in this one.