With a four-goal lead at half time, Pwllheli were well on their way to victory and a hat-trick from Jini Owen Hughes after the break proved the icing on the cake.
Seeking a third league triumph on the bounce, the visitors took an eighth-minute lead when Lois Thomas crossed from the left and Siân Moore tapped in her 14th goal of the season at the back post.
The away advantage was doubled on 15 when Jini Owen Hughes threaded a through ball for Lois Thomas, who slotted into the bottom-right corner.
It was soon three when Moore switched play from right to left, finding Thomas who struck home her second of the afternoon.
Awel Ellis got on the scoresheet before half time, heading home from a Jini Owen Hughes corner.
The second half saw Jini Owen Hughes take centre stage, first making it 5-0 on 56 minutes with a screamer into the top-left corner from around 20 yards out.
Former Pwllheli midfielder Katie Bowe pulled one back for Caernarfon on 70, Jordan Roberts assisting, but a sixth arrived for the visitors when Jini Owen Hughes completed her double – her 50th senior goal as a Pwllheli player on her 46th appearance.
And it got better for Hughes two minutes later when she converted a penalty awarded for handball.
Sub Megan Williams followed up her hat-trick from last week by bagging a consolation second for the Cofis in added time.
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