Goals from Tom Chamberlain and Nathan Williams within the first eight minutes, then a third by Sam Roberts in the second half clinched the points for Rhydymwyn against nine-man United.
Holywell endured a disastrous start when they had Dylan Hough red-carded in just the fourth minute.
Jac Williams also walked for the visitors with 82 on the clock for a second yellow.
The win lifted Rhydymwyn up to fifth.
Sixteen-year-old Alex Jones netted five times on his full senior debut for Caerwys in a double-figure drubbing of Skippy.
Jones struck on 14, 17, 25 (penalty), 46 and 59 minutes for the visitors, Michael Guest and Jack Smallman adding two each and Kieron Day also on the mark.
Thomas Eyes, Craig Worthington (2), Luca Nardo (2), Daniel Woosey, Nathan Jones and Kieran Edwards shared the goals in this away team rout.
Four goals in the final 20 minutes won this one for Lex.
Ricky Evans, Finley Dyer, Jason Edwards and Kian Davies were all on the mark.
A ninth win in 10 outings for Championship side Gronant at the expense of Premier Division opponents.
Gary Fazackerley and Daniel Price put the hosts two-up before Mykel Woollett pulled one back.
Lucky 13 for Rhostyllen but not so for the hosts Bellevue.
William Roberts and Ben Duffy both bagged hat-tricks for the Premier high-flyers, Samuel Chesters and Liam Sklenar added a brace apiece and there was one each for Tom Douglas, Drew Wickens and Jackson Pickford-Williams.
The Park took the honours in Friday night’s battle, John Edwards, Harry Gregory (2) and Mikey Latham splitting the home goals, David Jones and Shaun Edwards-Stanton responding.
A magnificent seventh straight win put Corwen top of the Premier.
Owen Cordiner (2), Alex Webster, Henry Evans and Joseph Ephraim guided the hosts to the points, Ryan Price Jones with a late consolation pair for the visitors, one a penalty.
Sam Giles struck four times for leaders Acton in a dozen-goal salvo at Brymbo.
There was a double apiece for Andy Bithell, Ryan Jones and Dale Williams, while Luke Pugh and Lewis Edwards (pen) added the rest,
James Williams (2) and Joseph Doyle-Davies were on target for third-place Plas in a hard-fought win over Aston Park.
Goals from Andy Cook and Lewis Jones kept the visitors in touch right till the end.
Seven for Caerwys Reserves on a goal-packed afternoon, Nathan Large (2), Lewis Harrison, Jack Wakeman (2), Shane Wellings and Connor Gorman combining with the goals, Kian Harrison with Corwen’s sole net-finder.
Kobie Betts (2) and George Davies delivered the goals that mattered for winners Mynydd Isa.
Joshua Venables’ hat trick, including a penalty, was not quite enough to bank the points for champions Queen’s Park Reserves.
Town grabbed a point thanks to replies from Callum Woods, Damon Bradley and Alexander Jones.
Michael Parry and George Baxter notched first-half goals that were sufficient to deliver Lex victory, Ryan Jones hitting back for Greenfield with 79 gone, but that was as good as it got for the visitors.
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